Big Mouth Teenage friends find their lives upended by the wonders and horrors of puberty in this edgy comedy from real-life pals Nick Kroll and Andrew Goldberg. Details Casts Season Lists Title Big Mouth Genres Animation Comedy First Air Date 2017-09-29 Last Air Date 2018-10-05 Episode Runtime 00 Hours 27 Minutes Total Season(s) 3 Total Episode(s) on All Seasons 21 Runtime 27 Production Companies Netflix Nick Kroll... Nick Birch / Hormone Mons... John Mulaney... Andrew Glouberman (voice)... Jessi Klein... Jessi Glaser (voice)... Jason Mantzoukas... Jay Bilzerian (voice)... Jenny Slate... Missy Foreman-Greenwald (... Fred Armisen... Elliot Birch (voice)... Jordan Peele... Ghost of Duke Ellington (... Maya Rudolph... Diane Birch / Hormone Mon... Season 1 10 Episode(s) 2017-09-29 Season 2 10 Episode(s) 2018-10-05 Season 3 1 Episode(s) 2019-02-08